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Individual response in patient's effort and driving pressure to variations in assistance during pressure support ventilation.

Mattia DocciEmanuele RezoagliMaddalena Teggia-DroghiAndrea CoppadoroMatteo PozziAlice GrassiIsabella BianchiGiuseppe FotiGiacomo Bellani
Published in: Annals of intensive care (2023)
Patients react to a decrease in PSV by increasing inspiratory effort-as estimated by PMI-keeping Vt and ∆P on a desired value, therefore, limiting the clinician's ability to modulate them. PMI appears a valuable index to assess the point of ventilatory overassistance when patients lose control over Vt like in a pressure-control mode. The measurement of Crs in PSV is constant-likely suggesting reliability-independently from the level of assistance and patient's effort.
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