Leptin-Melanocortin pathway variants and gastric emptying in patients with obesity.

Lizeth CifuentesWissam GhusnAlejandro CamposJoshua T BublitzMaria Daniela HurtadoJanet OlsonAndres Acosta

Published in: Neurogastroenterology and motility (2024)

Carriers of heterozygous variants in the Leptin-MC4R pathway had a delayed GE compared to noncarriers. These findings point the important relationship between the Leptin-MC4R pathway and gastric motility.

Keyphrases

metabolic syndrome
insulin resistance
weight loss
gene expression
adipose tissue
skeletal muscle
staphylococcus aureus
cystic fibrosis