Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast.

Conor P YoungCory HillyerKarsten HokampDarren J FitzpatrickNikifor K KonstantinovJacqueline S WeltyScott A NessMargaret Werner-WashburneAlastair B FlemingMary Ann Osley

Published in: BMC genomics (2017)

The data suggest that the transcript profile and histone methylation marks in quiescent cells were established both in growing cells and during the development of quiescence and then retained in these cells. Together, this might ensure that quiescent cells can rapidly adapt to a changing environment to resume growth.

Keyphrases

induced apoptosis
cell cycle arrest
dna methylation
endoplasmic reticulum stress
gene expression
oxidative stress
machine learning
genome wide
cell proliferation
single cell
artificial intelligence
pi k akt
rna seq