Contribution of skeletal muscular glycine to rapid antidepressant effects of ketamine in an inflammation-induced mouse model of depression.

Niannian HuangYue WangGaofeng ZhanFan YuShan LiDongyu HuaRiyue JiangShiyong LiYeshun WuLing YangBin ZhuFei HuaAilin LuoChun Yang

Published in: Psychopharmacology (2019)

Our findings suggest that skeletal muscular glycine contributes to the antidepressant effects of ketamine in inflammation. Effective strategies for improving skeletal muscular glycine levels may be a novel approach to depression treatment.

Keyphrases

resistance training
oxidative stress
mouse model
major depressive disorder
depressive symptoms
diabetic rats
sleep quality
pain management
high glucose
body composition
high intensity
bipolar disorder