The Feasibility, Tolerability, and Safety of Administering a Very High Alcohol Dose to Drinkers with Alcohol Use Disorder.

Ashley A VenaMeghan HoweDaniel J FridbergDingcai CaoAndrea C King

Published in: Alcoholism, clinical and experimental research (2020)

Results support the feasibility, tolerability, and safety of administering a very high alcohol dose to young adult drinkers with AUD within the context of a well-validated laboratory alcohol challenge paradigm. Utilizing an alcohol dose more consistent with naturalistic drinking patterns may foster greater ecological validity of laboratory paradigms for persons with moderate to severe AUD.

Keyphrases

alcohol consumption
alcohol use disorder
young adults
open label
climate change
high intensity
double blind
risk assessment
study protocol
childhood cancer