Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC-MS and ion mobility enabled HILIC-MS.
Adam M KingLauren G MullinIan D WilsonMuireann CoenPaul D RainvilleRobert S PlumbLee A GethingsGarth MakerRobert TrengovePublished in: Metabolomics : Official journal of the Metabolomic Society (2019)
A rapid metabolic profiling method for the analysis of polar metabolites has been developed. The method has the advantages of speed and both reducing sample and solvent consumption compared to conventional profiling methods. The addition of IMS added an additional dimension for feature detection and the identification of metabolites.