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Optimizing whole blood storage: hemostatic function of 35-day stored product in CPD, CP2D, and CPDA-1 anticoagulants.

Michael Adam MeledeoGrantham C PeltierColby S McIntoshJames A BynumAndrew P Cap
Published in: Transfusion (2019)
WB is easier to collect, store, and transfuse. WB provides platelets, an oft-neglected, critical resuscitation component, but their individual numbers decline as aggregates appear, resulting in diminished coagulation response. WB has better performance in these assays when examined at earlier time points, but expirations designated to specific anticoagulants appear arbitrary for hemostatic functionality, as little changes beyond 21 days regardless of anticoagulant.
Keyphrases
  • cardiac arrest
  • venous thromboembolism
  • high throughput
  • room temperature
  • septic shock