Localized Non-Metastatic Sarcomatoid Renal Cell Carcinoma: A 31 Year Externally Verified Study.
Kyle A BlumAndrew W SilagyAndrea KnezevicStanley WengAlan WangRoy ManoJulian MarconRenzo G DiNataleAlejandro SanchezSatish TickooSounak GuptaRobert MotzerNaomi B HaasSe Eun KimRobert G UzzoJonathan A ColemanA Ari HakimiPaul RussoPublished in: BJU international (2023)
Localized sRCC has worse CSS compared to grade-4 non-sRCC at every stage. Negative survival predictors included positive-margins, higher pathological stage, use of MIS, and non-ccRCC histology. sRCC is an aggressive variant even at low stages requiring vigilant surveillance and possible inclusion in adjuvant therapy trials.