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Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems.

Jan Sher AkmalMika SalmiAntti Aarni MäkitieRoy BjörkstrandJouni Partanen
Published in: Journal of functional biomaterials (2018)
The purpose of this study is to demonstrate the ability of additive manufacturing, also known as 3D printing, to produce effective drug delivery devices and implants that are both identifiable, as well as traceable. Drug delivery devices can potentially be used for drug release in the direct vicinity of target tissues or the selected medication route in a patient-specific manner as required. The identification and traceability of additively manufactured implants can be administered through radiofrequency identification systems. The focus of this study is to explore how embedded medication and sensors can be added in different additive manufacturing processes. The concept is extended to biomaterials with the help of the literature. As a result of this study, a patient-specific drug delivery device can be custom-designed and additively manufactured in the form of an implant that can identify, trace, and dispense a drug to the vicinity of a selected target tissue as a patient-specific function of time for bodily treatment and restoration.
Keyphrases
  • drug delivery
  • drug release
  • healthcare
  • primary care
  • systematic review
  • cancer therapy
  • gene expression
  • wastewater treatment
  • combination therapy
  • electronic health record
  • catheter ablation