Urodynamic measurements reflect physiological bladder function in rats.
Marc P SchneiderAndrea M SartoriJuliane TampéSelina MoorsAnne K EngmannBenjamin V IneichenAnna-Sophie HoferMartin E SchwabThomas M M KesslerPublished in: Neurourology and urodynamics (2017)
Lower urinary tract function assessed by metabolic cage or by urodynamic meaurements in fully awake rats was indistinguishable. Thus, catheter implantation did not significantly change physiological bladder function. This shows that urodynamic measurements in awake animals are an appropriate approach to study lower urinary tract function in health and disease in animal models, directly paralleling the human diagnostic procedures.