The efficacy and safety of concentrated herbal extract granules, YH1, as an add-on medication in poorly controlled type 2 diabetes: A randomized, double-blind, placebo-controlled pilot trial.
Yueh-Hsiang HuangSzu-Tah ChenFeng-Hsuan LiuSheng-Hwu HsiehChia-Hung LinMiaw-Jene LiouChih-Ching WangChung-Huei HuangGeng-Hao LiuJr-Rung LinLan-Yan YangTzu-Yang HsuMing-Chung LeeChun-Teng HuangYi-Hong WuPublished in: PloS one (2019)
This pilot study indicates that YH1 together with OHAs can improve hypoglycemic action and β-cell function in overweight/obese patients with poorly controlled type 2 diabetes. YH1 is a safe add-on medication for OHAs and has beneficial effects on weight control and lipid metabolism. A larger study population with longer treatment and follow-up periods is required for further verification.
Keyphrases
- phase ii study
- placebo controlled
- type diabetes
- double blind
- weight loss
- glycemic control
- open label
- phase ii
- phase iii
- study protocol
- clinical trial
- healthcare
- physical activity
- cardiovascular disease
- insulin resistance
- body mass index
- adipose tissue
- weight gain
- oxidative stress
- emergency department
- radiation therapy
- rectal cancer
- replacement therapy