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Association of serum CTRP4 levels with vascular endothelial function in patients with type 2 diabetes mellitus: CTRP4 ameliorating inflammation, proliferation and migration in human umbilical vein endothelial cells.

Jie GaoMai Re YanMu RouziHuihui ZhangXinghua CaiBilin XuJun LuTao Lei
Published in: Acta diabetologica (2024)
Serum CTRP4 concentrations were negatively associated with FMD. CTRP4 alleviated proliferation, migration and inflammation in HUVECs through the suppression of NF-κB and STAT3 signaling pathways.
Keyphrases
  • signaling pathway
  • oxidative stress
  • endothelial cells
  • pi k akt
  • epithelial mesenchymal transition
  • induced apoptosis
  • lps induced
  • nuclear factor
  • inflammatory response
  • high glucose
  • endoplasmic reticulum stress