Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage.
Keisha AlexanderKelsey HazeghFang FangDerek SincharJoseph E KissGrier P PageAngelo D'AlessandroTamir KaniasPublished in: Transfusion (2020)
These observations provide new insights into testosterone-mediated changes in RBC metabolome and biology that may impact the storage capacity and posttransfusion efficacy of RBCs from TRT donors.