Sleep architecture is associated with core symptom severity in autism spectrum disorder.

Makoto KawaiCasey BuckChristina F ChickLauren AnkerLisa TalbotLogan Douglas SchneiderOmer LinkovskiIsabelle CottoKai Parker-FongJennifer M PhillipsAntonio HardanJoachim HallmayerRuth O'Hara

Published in: Sleep (2022)

Increased SWS and reduced REM sleep ratio differentiated ASD from TD. However, only increased SWS was associated with more severe core ASD symptoms. Increased SWS may reflect neuronal immaturity specific to ASD in this age group. These findings may inform the underlying mechanisms of clinical symptoms observed in children and adolescents with ASD.

Keyphrases

autism spectrum disorder
attention deficit hyperactivity disorder
intellectual disability
sleep quality
physical activity
depressive symptoms
early onset
drug induced