BMP4 is insufficient to differentiate umbilical cord mesenchymal stem cells into germ cell-like cells in vitro.
Pengbo WangHuanhuan HuXinyi LiRuiyun ZhangHongbin ChengHaixia QinGuojie JiHuigen FengYanli LiuJuntang LinPublished in: Ginekologia polska (2022)
The differentiation of MSCs into GC-like cells is rather complex, and BMP4 alone is insufficient to induce UcMSCs to differentiate into GC-like cells, regardless of protein level or gene expression level.