Herpes simplex virus PCR in 2230 explanted corneal buttons.
Gábor TóthBarbara Berkó-GöttelBerthold SeitzAchim LangenbucherTanja StachonMilán Tamás PluzsikZoltán Zsolt NagySigrun SmolaNóra SzentmáryPublished in: Acta ophthalmologica (2021)
Our data demonstrate that a positive clinical history of HSK is related to HSV PCR positivity in about every 2.8th patient. In addition, about every 66th explanted corneal tissue is HSV PCR-positive despite the lack of clinical suspicion. These patients may need additional local/systemic antiviral treatment to avoid newly acquired HSK following penetrating keratoplasty.