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Clinical features of systemic lupus erythematosus patients with splenomegaly: focussed on the cytopenias.

So Hye NamHan-Seung ParkSoo Min AhnJi Seon OhYong-Gil KimChang-Keun LeeBin YooSeokchan Hong
Published in: Internal medicine journal (2023)
This study aimed to investigate the clinical features of splenomegaly, mainly focussing on cytopenia, in patients with systemic lupus erythematosus (SLE). Cytopenia was commonly observed in 111 SLE patients with splenomegaly (n = 79, 71.2%). During the follow-up period, two patients developed haematologic malignancy after the diagnosis of SLE and splenomegaly, but no patients experienced severe complications (e.g. splenic rupture) related to splenomegaly.
Keyphrases
  • systemic lupus erythematosus
  • end stage renal disease
  • disease activity
  • ejection fraction
  • newly diagnosed
  • prognostic factors
  • peritoneal dialysis
  • rheumatoid arthritis