Efficacy and safety of abobotulinumtoxinA for upper limb spasticity in children with cerebral palsy: a randomized repeat-treatment study.
Mauricio R DelgadoAnn TiltonJorge Carranza-Del RíoDursun NigarMarcin BonikowskiResa AydinIwona Maciag-TymeckaJoyce OleszekEdward DabrowskiAnne-Sophie GrandoulierPhilippe Picautnull nullPublished in: Developmental medicine and child neurology (2020)
AbobotulinumtoxinA injections significantly reduced upper limb spasticity in children with cerebral palsy. Children treated with abobotulinumtoxinA and targeted home exercises showed global improvement and goal attainment. Benefits were sustained over 1 year with repeat cycles of abobotulinumtoxinA and home exercises. AbobotulinumtoxinA injections into the upper limb were well tolerated over 1 year.