Two new flavone glycosides from the leaves of Ochna afzelii Oliv. (Ochnaceae).

Two new glycosylflavones, 6''- O -acetyl-8- C - β - D -galactopyranosylchrysoeriol ( 1 ) and 8- C - β - D -galactopyranosylchrysoeriol ( 2 ) were isolated from the methanol extract of the leaves of Ochna afzelii Oliv., along with four known compounds namely 8- C - β - D -galactopyranosylapigenin ( 3 ), ochnaflavone ( 4 ), sitosterol-3- O - β-D- glucopyranoside ( 5 ) and D -mannitol ( 6 ). Isolation was performed chromatographically and the structures of the purified compounds were elucidated by analyzing their spectroscopic and mass spectrometric data. The antibacterial activity of extract, fractions, and compounds 1 - 4 was evaluated using broth microdilution method against Gram-positive and Gram-negative bacteria while the antioxidant capacity was performed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and the ferric reducing antioxidant power (FRAP) methods. The new flavones ( 1 and 2 ) displayed moderate antibacterial activities (MIC = 32 - 64 µg/mL) and weak antioxidant properties.