Multivariable modeling of biomarker data from the phase 1 Foundation for the NIH Osteoarthritis Biomarkers Consortium.
Leticia A DevezaDavid John HunterJamie E CollinsElena LosinaMichael C NevittFrank W RoemerAli GuermaziMichael A BowesErik B DamFelix EcksteinJohn A LynchJeffrey N KatzChian K KwohSteve HoffmannVirginia B KrausPublished in: Arthritis care & research (2021)
This study highlights the combination of biomarkers with potential prognostic utility in OA disease-modifying trials. Properly qualified, these biomarkers could be used to enrich future trials with participants likely to progress.