Shared Genetics and Comorbid Genes of Amyotrophic Lateral Sclerosis and Parkinson's Disease.

Ye TianGuochen MaHaoqi LiYaxian ZengSiquan ZhouXiaoyu WangShufang ShanYujie XuJingyuan XiongGuo Cheng

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

Our work demonstrates shared genetic architecture between ALS and PD, reports new pleiotropic genes, and sheds light on the comorbid mechanism. © 2023 International Parkinson and Movement Disorder Society.

Keyphrases

amyotrophic lateral sclerosis
genome wide
bioinformatics analysis
genome wide identification
dna methylation
copy number
genome wide analysis
transcription factor
gene expression
electronic health record