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Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline.

Melissa LamarSue E LeurgansAlifiya KapasiLisa L BarnesPatricia A BoyleDavid A BennettKonstantinos ArfanakisJulie A Schneider
Published in: Stroke (2021)
Mixed CVD, more common than single CVD, is associated with cognitive decline, and distinct mixed CVD profiles show domain-specific associations with cognitive decline. CVD is not monolithic but consists of heterogenous person-specific combinations with distinct contributions to cognitive decline.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • white matter
  • ionic liquid
  • mass spectrometry
  • brain injury
  • liquid chromatography