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KLF11 is an independent negative prognostic factor for breast cancer from a cohort study and induces proliferation and inhibits apoptosis in vitro.

Lili LinKristina PfenderNina DitschChristina KuhnMartina RahmehLin PengElisa SchmoeckelDoris MayrFabian TrillschSven MahnerMirjana KesslerUdo JeschkeAnna Hester
Published in: Breast cancer (Tokyo, Japan) (2023)
Our study indicated that targeting KLF11 is an interesting therapeutic concept and further research could lead to a new therapeutic improvement in BC, especially in highly aggressive molecular subtypes.
Keyphrases
  • prognostic factors
  • transcription factor
  • oxidative stress
  • endoplasmic reticulum stress
  • signaling pathway
  • cancer therapy
  • childhood cancer
  • cell proliferation