KLF11 is an independent negative prognostic factor for breast cancer from a cohort study and induces proliferation and inhibits apoptosis in vitro.
Lili LinKristina PfenderNina DitschChristina KuhnMartina RahmehLin PengElisa SchmoeckelDoris MayrFabian TrillschSven MahnerMirjana KesslerUdo JeschkeAnna HesterPublished in: Breast cancer (Tokyo, Japan) (2023)
Our study indicated that targeting KLF11 is an interesting therapeutic concept and further research could lead to a new therapeutic improvement in BC, especially in highly aggressive molecular subtypes.