Minor Genetic Overlap Among Rheumatoid Arthritis, Myocardial Infarction, and Myocardial Infarction Risk Determinants.

Anton Öberg SysojevLars AlfredssonLars Klareskognull nullGilad N SilberbergSaedis SaevarsdottirLeonid PadyukovPatrik K E MagnussonJohan AsklingHelga Westerlind

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

Our findings indicate that genetic overlap between patients with RA and MI is minor. Furthermore, genetic overlap between RA and MI risk factors seem unlikely to provide a major contribution to the increased risk of MI observed in patients with RA.

Keyphrases

rheumatoid arthritis
disease activity
risk factors
genome wide
heart failure
ankylosing spondylitis
interstitial lung disease
copy number
left ventricular
gene expression
dna methylation
systemic sclerosis
atrial fibrillation