Adverse functional remodelling of the subpulmonary left ventricle in patients with a systemic right ventricle is associated with clinical outcome.

Beatrice Santens Frederik Helsen Alexander Van De Bruaene Pieter De MeesterAnne-Laure BudtsEls Troost Philip Moons Piet Claus Filip R Rega Jan Bogaert Werner Budts

Published in: European heart journal. Cardiovascular Imaging (2021)

NT-proBNP was by far the best prognostic marker for clinical outcome. Adverse remodelling with increase of LVEDVi and SVi of the subpulmonary LV at rest and during exercise were associated with worse clinical outcome. We theorize that remodelling of the subpulmonary ventricle might be an early sign of a failing sRV circulation.

Keyphrases

pulmonary artery
pulmonary hypertension
mitral valve
coronary artery
congenital heart disease
pulmonary arterial hypertension
high intensity
physical activity
adverse drug
resistance training
heart failure
electronic health record
atrial fibrillation