Oxidative Stress in Cardiac Tissue of Patients Undergoing Coronary Artery Bypass Graft Surgery: The Effects of Overweight and Obesity.
Yves GramlichAndreas DaiberKatja BuschmannMatthias OelzeChristian-Friedrich VahlThomas MünzelUlrich HinkPublished in: Oxidative medicine and cellular longevity (2018)
Increasing BMI in patients undergoing CABG is related to altered myocardial redox patterns, which indicates increased oxidative stress with inadequate antioxidant compensation. These changes suggest that the myocardium of obese patients suffering from coronary artery disease is more susceptible to cardiomyopathy and possible damage by ischemia and reperfusion, for example, during cardiac surgery.
Keyphrases
- coronary artery bypass
- oxidative stress
- patients undergoing
- obese patients
- percutaneous coronary intervention
- coronary artery disease
- cardiac surgery
- bariatric surgery
- acute myocardial infarction
- left ventricular
- diabetic rats
- ischemia reperfusion injury
- gastric bypass
- dna damage
- roux en y gastric bypass
- induced apoptosis
- coronary artery bypass grafting
- heart failure
- acute coronary syndrome
- acute kidney injury
- body mass index
- cardiovascular events
- cerebral ischemia
- weight loss
- type diabetes
- minimally invasive
- acute ischemic stroke
- aortic valve
- physical activity
- subarachnoid hemorrhage
- blood brain barrier
- aortic stenosis