Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania.

Peter M MbeleleChristian UtpatelElingarami SauliEmmanuel Abraham MpolyaBeatrice K MutayobaIvan BarilarViola DreyerMatthias MerkerMargaretha L SarikoBuliga M SwemaBlandina T MmbagaJean GratzKennedy K AddoMichel PletschetteStefan NiemannEric R HouptStellah G MpagamaScott K Heysell

Published in: JAC-antimicrobial resistance (2022)

WGS-based drug resistance prediction worked well to rule-in phenotypic drug resistance and the absence of second-line drug resistance-mediating mutations has the potential to guide the design of RR/MDR-TB regimens in the future.

Keyphrases

mycobacterium tuberculosis
multidrug resistant
acinetobacter baumannii
gram negative
pulmonary tuberculosis
escherichia coli
risk assessment
cystic fibrosis
klebsiella pneumoniae