Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands: A prospective cohort study.

Marit J VAN Gils H A Ayesha Lavell Karlijn van der Straten Brent Appelman Ilja BontjerMeliawati PonimanJudith A BurgerMelissa OomenJoey H BouhuijsLonneke A van VughtMarleen A Slim Michiel Schinkel Elke Wynberg Hugo D G van Willigen Marloes GrobbenKhadija TejjaniJacqueline van RijswijkJonne L SnitselaarTom G Canielsnull nullAlexander P. J. VlaarMaria PrinsMenno D de Jong Godelieve J de BreeJonne J SikkensMarije K Bomers Rogier W Sanders

Published in: PLoS medicine (2022)

Overall, this study shows that the mRNA vaccines appear superior to adenovirus vector-based vaccines in inducing neutralizing antibodies against VOCs four weeks after initial vaccination and after booster vaccination, which implies the use of mRNA vaccines for both initial and booster vaccination.

Keyphrases

sars cov
respiratory syndrome coronavirus
copy number
coronavirus disease
genome wide