Amotosalen and ultraviolet A light treatment efficiently inactivates severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human plasma.

Esam Ibraheem Azhar Salwa I HindawiSherif A El-KafrawyAhmed M HassanAhmed M TolahThamir A AlandijanyLeena H BajraiGhazi A Damanhouri

Published in: Vox sanguinis (2020)

Amotosalen/UVA light treatment of SARS-CoV-2 spiked human plasma units efficiently and completely inactivated >3·32 ± 0·2 log of SARS-CoV-2 infectivity, showing that such treatment could minimize the risk of transfusion-related SARS-CoV-2 transmission.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
cardiac surgery
acute kidney injury
replacement therapy
drug induced