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Amotosalen and ultraviolet A light treatment efficiently inactivates severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human plasma.

Esam Ibraheem AzharSalwa I HindawiSherif A El-KafrawyAhmed M HassanAhmed M TolahThamir A AlandijanyLeena H BajraiGhazi A Damanhouri
Published in: Vox sanguinis (2020)
Amotosalen/UVA light treatment of SARS-CoV-2 spiked human plasma units efficiently and completely inactivated >3·32 ± 0·2 log of SARS-CoV-2 infectivity, showing that such treatment could minimize the risk of transfusion-related SARS-CoV-2 transmission.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease
  • cardiac surgery
  • acute kidney injury
  • replacement therapy
  • drug induced