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Polyglucosan body myopathy 1 may cause cognitive impairment: a case report from China.

Lin ChenNan WangWenbin HuXuen YuRenming YangYongzhu HanYan YanNa NianCongbo Sha
Published in: BMC musculoskeletal disorders (2021)
This case from China with a novel homozygous missense mutation in RBCK1 extends the phenotypic spectrum and geographical distribution of PGBM 1, which may cause cerebral white matter changes and cognitive impairment.
Keyphrases
  • cognitive impairment
  • white matter
  • subarachnoid hemorrhage
  • late onset
  • intellectual disability
  • multiple sclerosis
  • autism spectrum disorder
  • muscular dystrophy
  • brain injury