Genomic characterization of carbapenemase-producing Enterobacterales from Dhaka food markets unveils the spread of high-risk antimicrobial-resistant clones and plasmids co-carrying bla NDM and mcr-1.1 .
Tania Tabassum NisaYo SugawaraShigeto HamaguchiDan TakeuchiRyuichiro AbeEisuke KurodaMasatomo MoritaHui ZuoAkiko UedaIsao NishiNowrin HossainMd Mahmudul HasanMahbubul H SiddiqeeDaisaku NakataniKen NakataYukihiro AkedaPublished in: JAC-antimicrobial resistance (2024)
The analysis unveils a dynamic landscape of CPE dissemination in food markets, underscored by the proliferation of novel IncHI2 hybrid plasmids carrying both colistin- and carbapenem-resistance genes. This illuminates the ever-evolving landscape of antimicrobial resistance in Dhaka, urging us to confront its emergent challenges.
Keyphrases
- klebsiella pneumoniae
- antimicrobial resistance
- escherichia coli
- multidrug resistant
- single cell
- human health
- staphylococcus aureus
- signaling pathway
- acinetobacter baumannii
- genome wide
- drug resistant
- gram negative
- copy number
- risk assessment
- dna methylation
- genome wide identification
- climate change
- bioinformatics analysis
- cystic fibrosis