Relationship between 'on-treatment platelet reactivity', shear stress, and micro-embolic signals in asymptomatic and symptomatic carotid stenosis.
Stephen J X MurphyS T LimJ A KinsellaS TierneyB EganT M FeeleyS M MurphyR A WalshD R CollinsT CoughlanD O'NeillJ A HarbisonP MadhavanS M O'NeillM P ColganD CoxN MoranG HamiltonJ F MeaneyDominick J H McCabePublished in: Journal of neurology (2019)
Recently symptomatic moderate-severe carotid stenosis patients had a lower prevalence of aspirin-HTPR than their asymptomatic counterparts on the PFA-100®, likely related to higher aspirin doses. The prevalence of antiplatelet-HTPR was positively influenced by higher shear stress levels, but not MES status.
Keyphrases
- low dose
- end stage renal disease
- risk factors
- ejection fraction
- newly diagnosed
- chronic kidney disease
- antiplatelet therapy
- peritoneal dialysis
- type diabetes
- high intensity
- coronary artery disease
- cardiovascular disease
- patient reported outcomes
- replacement therapy
- combination therapy
- atrial fibrillation
- smoking cessation