Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro.

Vu Thuy Khanh Le-TrillingDenise MennerichCorinna SchulerRoman SaksonJulia K LillSiva Swapna KasarlaDominik KopczynskiStefan LorochYulia Flores-MartinezBenjamin KatschinskiKerstin WohlgemuthMatthias GunzerFolker MeyerPrasad PhapaleUlf DittmerAlbert SickmannMirko Trilling

Published in: BMC biology (2022)

In conclusion, herbal teas based on perilla and sage exhibit antiviral activity against SARS-CoV-2 including variants of concern such as Alpha, Beta, Delta, and Omicron, and we identified HMOX-1 as potential therapeutic target. Given that perilla and sage have been suggested as treatment options for various diseases, our dataset may constitute a valuable resource also for future research beyond virology.

Keyphrases

sars cov
respiratory syndrome coronavirus
copy number
gene expression
human health
genome wide