Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth.

Margherita ZamberlanAmandine BoeckxFlorian MullerFederica VinelliOlivier EkCaterina VianelloEmeline CoartKeitaro ShibataAurélie ChristianFrancesca GrespiMarta GiacomelloIngrid StrumanLuca ScorranoStéphanie Herkenne

Published in: Journal of experimental & clinical cancer research : CR (2022)

Our data show that targeted inhibition of the mitochondrial fusion protein OPA1 curtails TNBC growth and nominate OPA1 as a druggable target in TNBC.

Keyphrases

oxidative stress
electronic health record
big data
amino acid
binding protein
drug delivery
childhood cancer