Does leptin cause proximal gastric cancer in the obese? The role of serum leptin in the etiology of proximal gastric cancer.
Tomaz JagricGaja HladnikRok KolaricMarjeta DugonikEvgenija HomsakPublished in: Hormone molecular biology and clinical investigation (2023)
Serum levels of leptin were significantly elevated in patients with proximal gastric cancer, suggesting that the leptin's effect might be due to its systemic secretion. This might explain the higher incidence of proximal gastric cancer in obese patients. Elevated serum leptin levels were an independent prognostic factor.