Differential expression of Type I interferon and inflammatory genes in SARS-CoV-2-infected patients treated with monoclonal antibodies.

Luca MaddaloniLetizia SantinelliGinevra BuganiElio G CacciolaAlessandro LazzaroChiara M LofaroSara CaiazzoFederica FrascaMatteo FracellaCamilla AjassaCristiana LeanzaAnna NapoliLilia CintiAurelia GaetaGuido AntonelliGiancarlo CeccarelliClaudio M MastroianniCarolina ScagnolariGabriella d'Ettorre

Published in: Immunity, inflammation and disease (2023)

These data suggest that anti-S vaccinated patients have increased levels of innate immune genes compared to unvaccinated ones. Also, gene expression changes in IFN genes after mAbs administration are different according to the vaccination status of patients.

Keyphrases

gene expression
end stage renal disease
sars cov
newly diagnosed
ejection fraction
chronic kidney disease
genome wide
prognostic factors
peritoneal dialysis
dna methylation
dendritic cells
machine learning