Fetal exposure to dichloroacetic acid and impaired cognitive function in the adulthood.
Yue WangWenbo JiangQiuying DongYue ZhaoYingying ChenChanghao SunGuoli SunPublished in: Brain and behavior (2020)
Taken together, these results above showed that oxidative stress, neuroinflammation response, and weakened synaptic plasticity in pups hippocampus induced by fetal exposure to DCA could damage the function of memory and cognition in the adulthood.
Keyphrases
- oxidative stress
- depressive symptoms
- cognitive impairment
- early life
- cerebral ischemia
- dna damage
- traumatic brain injury
- working memory
- ischemia reperfusion injury
- lipopolysaccharide induced
- diabetic rats
- induced apoptosis
- lps induced
- white matter
- prefrontal cortex
- multiple sclerosis
- inflammatory response
- signaling pathway
- heat shock