Chloroquinolone Carboxamide Derivatives as New Anti-HSV-1 Promising Drugs.
Mariana SouzaCamilly Pestana Pires de MeloLetícia Villafranca FaroLuciane Fragel-MadeiraViveca GiongoPaula Alvarez AbreuFernanda da Costa Santos BoechatDavid de Oliveira SilvaNathalia Motta de Carvalho TolentinoClaudio Cesar Cirne-SantosCaroline de Souza BarrosHelena Carla CastroMarcos Costa de SouzaMaria Cecília Bastos Vieira de SouzaIzabel Christina Nunes de Palmer PaixãoPublished in: Current topics in medicinal chemistry (2023)
Although the inhibition activities of chloroquinolone carboxamide derivatives were lower than acyclovir, they showed different modes of action in comparison to the drugs currently available. These findings encourage us to continue pre-clinical studies for the development of new anti-HSV-1 agents.
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