Fruit intake, genetic risk and type 2 diabetes: a population-based gene-diet interaction analysis.

Xu JiaLiping XuanHuajie DaiWen ZhuChanjuan DengTiange WangMian LiZhiyun ZhaoYu XuJieli LuYufang BiWeiqing WangYuhong ChenYanan HouGuang Ning

Published in: European journal of nutrition (2021)

Fruit intakes interact with the genetic predisposition of T2D on the risk of diabetes and related glucose metabolic traits. Fruit intake alleviates the association between genetic predisposition of T2D and the risk of diabetes; the association of fruit intake with a lower risk of diabetes was more prominent in population with a stronger genetic predisposition of T2D.

Keyphrases

type diabetes
genome wide
glycemic control
cardiovascular disease
copy number
dna methylation
insulin resistance
gene expression
mouse model
body mass index