Login / Signup

Prognostic value of pretreatment systemic immune-inflammation index in patients with endometrial cancer: a meta-analysis.

Pengtian JiJunjun He
Published in: Biomarkers in medicine (2024)
Background: The present work focused on evaluating the systemic immune-inflammation index (SII) for its role in predicting endometrial cancer (EC) patient prognosis by meta-analysis. Methods: SII's role in predicting the prognosis of EC patients was analyzed by calculating combined hazard ratios (HRs) and 95% CIs. Results: As revealed by combined analysis, an increased SII predicted poor overall survival (HR = 2.01; 95% CI = 1.58-2.57; p < 0.001) as well as inferior progression-free survival (HR = 1.87; 95% CI = 1.36-2.58; p < 0.001) of EC. Conclusion: An increased SII score significantly predicted poor overall survival and progression-free survival in subjects with EC. The SII is suitable for predicting short- and long-term prognoses of patients with EC.
Keyphrases
  • free survival
  • endometrial cancer
  • systematic review
  • end stage renal disease
  • oxidative stress
  • ejection fraction
  • chronic kidney disease
  • peritoneal dialysis
  • prognostic factors
  • case control