Development of a Novel Tool to Assess the Impact of Itching in Pediatric Cholestasis.

Binita M. Kamath Linda Abetz-Webb Ciara Kennedy Bonnie Hepburn Martha Gauthier Nathan Johnson Sharon Medendorp Alejandro Dorenbaum Lora Todorova Benjamin L Shneider

Published in: The patient (2018)

Itching was the most bothersome ALGS symptom reported by study participants. We have developed the ItchRO(Patient) and ItchRO(Observer) to assess itching in children with ALGS and other cholestatic liver diseases. These diaries are being validated for use in clinical trials.

Keyphrases

clinical trial
liver injury
drug induced
young adults
phase ii
study protocol