Circulating p16-Positive and p16-Negative Tumor Cells Serve as Independent Prognostic Indicators of Survival in Patients with Head and Neck Squamous Cell Carcinomas.

Pei-Hung ChangHung-Ming WangYung-Chia KuoLi-Yu LeeChia-Jung LiaoHsuan-Chih KuoCheng-Lung HsuChih-Hung LinSanger Hung-Chi LinPei-Wei HuangTyler Min-Hsien WuJason Chia-Hsun Hsieh

Published in: Journal of personalized medicine (2021)

The p16-positive and p16-negative CTCs could predict outcomes in HNSCC patients receiving definitive chemoradiotherapy. This non-invasive CTC test could help stratify the risk and prognosis before chemoradiotherapy in clinical practice and enable us to perform de-intensifying therapies.

Keyphrases

locally advanced
squamous cell
rectal cancer
circulating tumor cells
clinical practice
squamous cell carcinoma
radiation therapy
high grade
skeletal muscle
free survival
glycemic control