Traumatic brain injury-induced fear generalization in mice involves hippocampal memory trace dysfunction and is alleviated by ( R,S )-ketamine.
Josephine C McGowanLiliana R LadnerClaire X ShubeckJuliana TapiaChristina T LaGammaAmanda Anqueira-Gonz LezAriana DeFrancescoBriana K ChenHolly C HunsbergerEzra J SydnorRyan W LoganTzong-Shiue YuSteven G KernieChristine A DennyPublished in: bioRxiv : the preprint server for biology (2023)
)-ketamine. This work enhances our understanding of the neural basis of TBI-induced fear generalization and reveals potential therapeutic avenues for alleviating this symptom.