Polyphenol Extracts from Ziziphus jujuba Mill. "Junzao" Attenuates Ulcerative Colitis by Inhibiting the NLRP3 and MAPKs Signaling Pathways and Regulating Gut Microbiota Homeostasis in Mice.

Xiaobo WeiNi MaWen YangJinhu TianHuiyan LiuHaitian Fang

Published in: Molecular nutrition & food research (2024)

PERJ probably inhibits the development of UC by suppressing the NLRP3 and MAPKs signaling pathways and regulating gut microbiota homeostasis, and can be considered as a potential resource for preventing UC.

Keyphrases

signaling pathway
ulcerative colitis
pi k akt
induced apoptosis
epithelial mesenchymal transition
nlrp inflammasome
high fat diet induced
metabolic syndrome
skeletal muscle
adipose tissue