The effect of xylazine on intracranial pressure in anesthetized and standing horses.
Rachel A ReedKira L EpsteinJessica H BramskiKathryn A DiehlClare A RyanPublished in: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) (2021)
Administration of xylazine to anesthetized horses resulted in an increased CPP due to decreased ICP with concurrent increased MAP. Administration of xylazine to standing horses did not result in a change in ICP. However, with the increase in BPdop found in awake horses, it is likely that CPP would also increase in awake horses following xylazine administration.