Evaluation of viral co-infections among patients with community-associated Clostridioides difficile infection.
Lauren KorhonenJessica CohenNicole GregoricusMonica M FarleyRebecca PerlmutterStacy M HolzbauerGhinwa DumyatiZintars BeldavsAshley PaulickJan VinjéBrandi M LimbagoFernanda C LessaAlice Y GuhPublished in: PloS one (2020)
We assessed viral co-infections in 155 patients with community-associated Clostridioides difficile infection in five U.S. sites during December 2012-February 2013. Eighteen patients (12%) tested positive for norovirus (n = 10), adenovirus (n = 4), rotavirus (n = 3), or sapovirus (n = 1). Co-infected patients were more likely than non-co-infected patients to have nausea or vomiting (56% vs 31%; p = 0.04), suggesting that viral co-pathogens contributed to symptoms in some patients. There were no significant differences in prior healthcare or medication exposures or in CDI complications.
Keyphrases
- healthcare
- end stage renal disease
- sars cov
- ejection fraction
- chronic kidney disease
- newly diagnosed
- mental health
- prognostic factors
- peritoneal dialysis
- emergency department
- risk factors
- air pollution
- depressive symptoms
- social media
- multidrug resistant
- drug induced
- adverse drug
- health insurance
- antimicrobial resistance