Phospholipase Cβ3 Expressed in Mouse DRGs is Involved in Inflammatory and Postoperative Pain.

Susumu IdeTomoyuki Kawamata Kumiko IshidaSatoshi FuseyaTakashi IshidaYuki SugiyamaMikito Kawamata Satoshi Tanaka

Published in: Journal of pain research (2020)

Our results uncover a unique role of PLCβ3 in the development and maintenance of inflammatory pain induced by CFA application and in those of surgical incision-induced pain, although PLCβ3 does not play a major role in thermal nociception or mechanical nociception in normal conditions.

Keyphrases

postoperative pain
chronic pain
pain management
neuropathic pain
oxidative stress
diabetic rats
high glucose