Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancer.

An HuangZhuang SunHaopeng HongYong YangJiajia ChenZhaoya GaoJin Gu

Published in: Journal of translational medicine (2024)

We constructed novel hypoxia- and lactate metabolism-related molecular subtypes and revealed their immunological and genetic characteristics. We also developed an HLM scoring system that could be used to predict the prognosis and efficacy of immunotherapy in patients with CRC.

Keyphrases

endothelial cells
wastewater treatment
single molecule
single cell
genome wide
gene expression
copy number
dna methylation
drug induced