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Damage-associated molecular patterns as a mechanism of sevoflurane-induced neuroinflammation in neonatal rodents.

Young-Eun JoeJi Hae JunJu Eun OhJeong-Rim Lee
Published in: Korean journal of anesthesiology (2024)
In conclusion, 6 h of sevoflurane exposure induces neuroinflammation through the DAMPs pathway, HMGB-1, and galectin-3. Co-administration of ibuprofen reduced sevoflurane-induced neuroinflammation.
Keyphrases
  • traumatic brain injury
  • lipopolysaccharide induced
  • high glucose
  • lps induced
  • diabetic rats
  • cognitive impairment
  • cerebral ischemia
  • oxidative stress
  • drug induced
  • endothelial cells