Clinically Significant Cytochrome P450-Mediated Drug-Drug Interactions in Children Admitted to Intensive Care Units.

Tong LiBiwen HuLing YeZeying FengLongjian HuangChengjun GuoXiong WuWei TanYi WangGuo-Ping Yang Cheng-Xian Guo

Published in: International journal of clinical practice (2022)

Clinically significant cytochrome P450-mediated pDDIs existed in the children admitted to ICUs, and some of the pDDIs led to adverse clinical outcomes. The use of clinical decision support systems can guide clinical medication use, and clinical monitoring of patients' needs has to be enhanced.

Keyphrases

clinical decision support
end stage renal disease
intensive care unit
young adults
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
electronic health record
peritoneal dialysis
emergency department
patient reported outcomes